Side Effects of Abilify (Aripiprazole)
Abilify (aripiprazole) is an atypical antipsychotic used to treat various mental health conditions, including schizophrenia, bipolar disorder, and as an adjunct treatment for major depressive disorder. While it is effective for many, it can also cause a range of side effects, from mild to severe.
Common Side Effects:
- Nausea and Vomiting:
- Some individuals may experience mild to moderate nausea or vomiting, especially when starting the medication.
- Drowsiness and Fatigue:
- Drowsiness or feeling excessively tired is a common side effect. Some people may experience insomnia as well, making it hard to sleep.
- Weight Gain:
- Weight gain is often reported, though it tends to be less severe compared to other antipsychotic medications.
- Headaches:
- Headaches are another frequently reported side effect.
- Restlessness or Agitation:
- Akathisia, or a feeling of inner restlessness, can occur, leading to constant movement or inability to sit still.
- Dizziness:
- Some individuals may feel dizzy or lightheaded, particularly when standing up quickly (orthostatic hypotension).
Serious Side Effects:
- Tardive Dyskinesia:
- Long-term use of Abilify can lead to tardive dyskinesia, which causes involuntary movements, particularly of the face, lips, and tongue. This condition can be irreversible in some cases.
- Neuroleptic Malignant Syndrome (NMS):
- This rare but life-threatening condition is characterized by high fever, muscle stiffness, confusion, and rapid heart rate. NMS requires immediate medical attention.
- Suicidal Thoughts:
- Abilify has been associated with an increased risk of suicidal thoughts or behaviors, particularly in young adults under 24, especially during the first few months of treatment or dosage changes.
- Increased Blood Sugar (Hyperglycemia):
- Abilify may lead to increased blood sugar levels, which can worsen or trigger diabetes in some individuals. Symptoms of high blood sugar include excessive thirst, frequent urination, and fatigue.
- Seizures:
- In rare cases, Abilify can lower the seizure threshold, making individuals more prone to seizures.
- Heart Problems:
- Abilify may cause irregular heart rhythms (QT prolongation), which can lead to more serious heart complications. This risk is higher for individuals with existing heart conditions.
Who Should Avoid Abilify?
- People with a history of seizures, heart conditions, or diabetes should use Abilify cautiously and under medical supervision.
- Individuals with a known allergy to aripiprazole or any ingredients in Abilify should avoid the medication.
Monitoring:
- Regular monitoring of blood sugar, weight, and cholesterol levels is recommended during treatment with Abilify, especially for individuals at risk of metabolic changes.
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