The side effects of Accutane (isotretinoin) can begin relatively early in the treatment, typically within the first week to two weeks of starting the medication. The onset and intensity of side effects can vary based on the dose, individual sensitivity, and the length of treatment. Below is a general timeline of when common side effects may start:
1. First 1–2 Weeks:
- Dry Skin and Lips: One of the earliest side effects is dryness of the skin and lips. Many users report needing lip balms and moisturizers almost immediately after starting treatment.
- Nosebleeds: Dry nasal passages can lead to nosebleeds, which often begin within the first week of use.
- Mild Headaches: Some individuals experience headaches early in the treatment.
2. First Month:
- Worsening of Acne: It’s common for acne to worsen during the first month of Accutane treatment before it starts improving. This is known as an initial breakout or “purging.”
- Muscle and Joint Pain: Some users report muscle soreness or joint discomfort beginning a few weeks into treatment.
- Dry Eyes and Vision Changes: Dry eyes and temporary vision changes, such as blurred vision or difficulty seeing at night, can also emerge within the first month.
3. After the First Month:
- Chapped Lips and Severe Dryness: As the treatment progresses, dryness of the skin and lips may become more pronounced.
- Fatigue: Some individuals report fatigue or a general feeling of tiredness after a few weeks.
- Mental Health Changes: In rare cases, mood swings, anxiety, or depression may start appearing after several weeks of use.
Serious Side Effects:
- Liver Function and Cholesterol: Increases in liver enzymes and cholesterol levels may occur after a few weeks or months, which is why regular blood tests are recommended during treatment.
Management and Monitoring:
If any side effects are experienced, especially severe or persistent ones, it’s essential to consult a healthcare provider. Regular check-ups, blood tests, and lifestyle adjustments (such as using moisturizers and avoiding sun exposure) can help manage and monitor side effects during the course of treatment.
Sources:
- Cleveland Clinic: Provides information on Accutane side effects and monitoring during treatment.
- Mayo Clinic: Offers a detailed breakdown of side effects and how to manage them during Accutane use.
